PREDICTIVE TOXICOLOGY: MODELING CHEMICAL INDUCED TOXICOLOGICAL RESPONSE COMBINING CIRCULAR FINGERPRINTS WITH RANDOM FOREST AND SUPPORT VECTOR MACHINE

Modern drug discovery and toxicological research are under pressure, as the cost of developing and testing new chemicals for potential toxicological risk is rising.Extensive abc material evaluation of chemical products for potential adverse effects is a challenging task, due to the large number of chemicals and the possible hazardous effects on hum

PurposeIn earlier experiments in Nigeria, aqueous extract of Pleurotus tuber-regium (PT) had been shown to lower intra ocular pressure (IOP) in a feline model.The aim of the current study was to determine whether PT had the same or a similar IOP-lowering effect in ocularly normal non-human primates.MethodsFour monkeys were treated twice daily for 4

The SARS-CoV-2 coronavirus has been circulating among the world population for click here 3 years, infecting hundreds of millions of people.Numerous reports from all over the world indicate that the majority of infections are caused by the Omicron variant and its subvariants, which predominate over all the previously emerged variants.The genome of